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The Spinneret
Fall 2018
A ramé-hart Newsletter devoted to Coaxial, Triaxial, Quadaxial and Custom
Spinnerets used for Electrospinning and Related Applications

 

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Portable Electrospinning Device for Medical Applications
Novel methods are being developed that deliver active pharmaceutical ingredients to a wound site. Nanofibers are 10 - 200 times finer than our hair. The very small dimension gives rise to a wide range of innovations in medicine and other areas. Today nanofibers are used in drug delivery to control when and how active therapeutics are delivered and released in the body. However, successful translation of nanofibers for daily healthcare is still limited. One of the barriers to practical application is accessibility. At present, all the manufacturing methods are limited to equipment that is confined to the factory or laboratory - heavy and cumbersome to assemble and it requires training to operate. Medics and surgeons cannot use these tools wherever and whenever needed - in hospitals, war zones, underprivileged regions or in ambulances. Furthermore, therapeutic nanofibers are fragile and hard to transport from factory to the point-of-care; the therapeutics being delivered such as growth hormones can have a half-life within minutes, which means they could have expired when they reach the patient.


Electrospun Fibers Under Magnification

Researchers at University College London are developing a portable, simple-to-operate nanofiber technology which will enable point-of-care manufacturing and administration of therapeutics in micro-/nano-structures at the press of a button. If this method proves successful, then valuable time to treatment would be saved as agents designed to stop bleeding, prevent infection, reduce pain or promote healing could be administered quickly in a form which could be applied to a wide range of lesion architectures and areas. Indeed, a portable system could also be used in conflict situations, for patients with mobility difficulties being treated at home for conditions such as diabetic ulcer or for otherwise medically inaccessible regions, while the use of biodegradable polymer bases would allow the mesh to be resorbed over a period of time without damage to the lesion associated with dressing removal. In close partnership with industrial end-users, this project lays the foundation for the access and practical use of nanofibers in a wide range of therapeutic applications.1

Proudly, ramé-hart instrument company participates in the development of this and other novel electrospinning and electrospraying methods by being the world's leading supplier of custom spinnerets.

1 Gareth R. Williams, Bahijja T. Raimi-Abraham, C. J. Luo (2018), Nanofibres in Drug Delivery
 

What's New
Based on customer demand, we now offer cleaning wires for needles. Previously, we offered cleaning wires as a special order item. These wire kits, kept in stock, are made of Tungsten or Type 304 Spring-back Stainless Steel offering the most rugged and reliable method for unclogging any needle. Order here. Currently, two sizes are available. Also for cleaning needles, we now offer a Precision Needle File. See it here.
 

Regards,

Carl Clegg
Director of Sales
Phone 973-448-0305
www.customspinnerets.com
www.ramehart.com
Contact us

 


 

Visit ramé-hart on Facebook    Visit ramé-hart on Twitter    Watch ramé-hart Videos    Look at ramé-hart's pictures on Flickr    Subscribe to our Monthly Newsletter    Visit ramé-hart on Linkedin